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scRNA-seq Biocurator/Ontologist (Cambridge, UK)

We are seeking to recruit a new member to our team at the University of Cambridge to contribute to the FlyBase Drosophila database (https://flybase.org). If you are looking for a fulfilling, fly-related career away from the bench, and enjoy the challenge of organizing complex data and presenting it clearly and concisely, then this is the job for you!

A large and growing community of Drosophila biologists is producing single cell transcriptomic data with potentially high value to the research community. This includes both individual labs and also large-scale community efforts focussed on sharing and annotating single cell RNA sequencing (scRNA-seq) datasets covering the whole fly, such as Fly Cell Atlas (https://flycellatlas.org/). The successful applicant will work closely with the Gene Expression Team (https://www.ebi.ac.uk/about/people/irene-papatheodorou) at EMBL-EBI, in particular those members responsible for the Single Cell Expression Atlas (scAtlas) (https://www.ebi.ac.uk/gxa/sc/home), in order to maximise the usefulness of the scRNA-seq data to the community.

The work will include:

- Identifying and prioritising published Drosophila scRNA-seq datasets for curation

- Curation of scRNA-seq experimental metadata into the EMBL-EBI scAtlas and/or FlyBase as appropriate

- Working with biocurators and software developers at FlyBase and the EMBL-EBI scAtlas to: harmonise the scRNA-seq data models used at each database, provide access to scRNA-seq data on FlyBase, add links between FlyBase and the scAtlas

- Extending the Drosophila Anatomy Ontology as needed to provide accurate terms for annotation of scRNA-seq data

- Working with EMBL-EBI Gene Expression Team members to help develop interactive fly anatomograms.


Closing date: 4th November 2020

More details and how to apply info: http://www.jobs.cam.ac.uk/job/27175/