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This gene article is a stub. It has been seeded with an automatically generated summary from FlyBase through release FB2016_05. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Has FlyBase identifier::FBgn0004364.html Dmel\18w.

Symbol Dmel\18w
Name Has current name::18 wheeler
Species Has genus::Drosophila Has species::melanogaster
Annotation symbol Has current annotation symbol::CG8896
FlyBase ID Has FlyBase identifier::FBgn0004364

The gene 18 wheeler is referred to in FlyBase by the symbol Dmel\18w (CG8896, FBgn0004364). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: transmembrane signaling receptor activity. There is experimental evidence that it is involved in the biological process: immune response; cell adhesion; anatomical structure morphogenesis; antibacterial humoral response. 22 alleles are reported. The phenotypes of these alleles are annotated with: leg; eye; wing disc; antenna; adult abdomen; haltere; mesothoracic tergum; wing; ventral thoracic disc. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal; Interleukin-1 receptor, type I/Toll precursor; Leucine rich repeat 5; Leucine-rich repeat; Leucine-rich repeat, typical subtype; Leucine-rich repeat-containing N-terminal; Toll/interleukin-1 receptor homology (TIR) domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval trachea, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult hindgut, adult heart, adult fat body, adult salivary gland, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626509_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of 18w. Gene sequence location is 2R:15999016..16004437.