FlyBase:Human Disease Model Report

Last Updated:

Introduction

General Information

Name	The valid full name that is used in FlyBase for the Human Disease Model.
FlyBase ID	The Primary FlyBase identifier number of the human disease, used to uniquely identify the Human Disease Model in the database.
Disease Ontology ID	Links to Disease Ontology term report in the Vocabularies tool.
Parent Disease	field text
OMIM	field text
Parent Disease DOID	field text

Overview

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Disease Summary Information

Parent Disease Summary

OMIM report	field text
Symptoms and phenotype	field text
Genetics	field text
Cellular phenotype and pathology	field text
Molecular information	field text
External links	field text
Disease synonyms	field text

Related Diseases

Related human health report(s)

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Related Specific Diseases

OMIM phenotypic series

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A table that consists of four columns:

Disease - Consists of OMIM symbol, links to OMIM phenotype report.

Associated Human gene(s) - Consists of OMIM symbol, links to OMIM genotype report.

Drosophila model - Consists of valid full name that is used in FlyBase for the disease, links to Human Disease Model Report.

Human transgene in Drosophila - "y" or no entry; has the human ortholog been transgenically expressed in flies.

Ortholog Information

Human gene (HGNC)	field text
Human gene (FlyBase)	field text
D. melanogaster ortholog (based on DIOPT)	field text
Comments on ortholog(s)	field text
Other mammalian ortholog(s) used	field text

D. melanogaster Gene Information

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Synthetic Gene(s) Used

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Experimental Findings

Summary

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Human Disease Wiki (Experimental Findings)

User Contributed Commentary

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Description of Experiments

Mammalian transgenics: heterologous rescue	field text
Mammalian transgenics: transgenic phenotype	field text
Mammalian transgenics: interactions	field text
Mammalian transgenics: pertubations and treatments	field text
Drosophila genes: relevant phenotypes	field text
Drosophila genes: interactions	field text
Drosophila genes: pertubations and treatments	field text
Drosophila recombinant constructs: phenotype or rescue	field text
Additional information	field text
Proposed mechanisms	field text

Summary of Physical Interactions

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Alleles Reported to Model Human Disease (Disease Ontology)

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Genetic Tools, Stocks and Reagents

Sources of Stocks

Bloomington Stock Center Disease Page

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Selected mammalian transgenes

A table that consists of three columns:

Allele - field text

Transgene - field text

Publicly Available Stocks - field text

Selected Drosophila transgenes

A table that consists of three columns:

Allele - field text

Transgene - field text

Publicly Available Stocks - field text

RNAi constructs available

A table that consists of three columns:

Allele - field text

Transgene - field text

Publicly Available Stocks - field text

Selected Drosophila classical alleles

A table that consists of four columns:

Allele - field text

Allele class - field text

Mutagen - field text

Publicly Available Stocks - field text

References

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