Difference between revisions of "FlyBase:Signaling Pathway Report"
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| + | The <b>‘Gene Group - Pathway Report’</b> is a sub-category of our Gene Group resource, which houses functional collections of genes such as complexes and gene families. <b>‘Pathway Reports’</b> list genes that have been experimentally shown to act within a pathway or to regulate a pathway. The reports are tailored to display information that may be useful to understanding the role of a particular pathway component or regulator: membership of other Gene Groups, experimentally characterized molecular functions and supporting research papers. Useful links to external resources and publications are provided, as well as options for export and orthology tools. | ||
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| + | The <b>‘Pathway Report’</b> pages are a prelude to what will become a rich resource for researchers to access the curated data on pathway members and regulators. Our first aim is to make the list of curated pathway genes available for immediate use and review. Over 2018, we will add more pathways based on a first-pass review of the research literature. We welcome any feedback <http://flybase.org/contact/email> to help improve the usefulness and accuracy of these gene lists. | ||
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| + | All Gene Group Pathways in FlyBase are compiled manually by FlyBase curators, based on research literature, using standards for inclusion agreed by the Gene Ontology consortium. The number of research papers that have been used as evidence for membership gene is shown in the Members table. These references can be viewed as a hitlist by clicking on the number. The number of pathway references associated with a gene may also help researchers weigh the evidence behind its inclusion. All source references are given in full at the foot of the page. | ||
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| + | Buttons are provided to export these member genes to our ‘Batch Download’ tool, if you wish to download associated data (phenotypes, expression data, protein interactions etc.), or to a standard FlyBase HitList, if you want to further refine or analyse the gene list, or to our ortholog tool, DIOPT, to obtain a list of predicted orthologs. | ||
Revision as of 12:34, 15 June 2018
Last Updated: 15 June 2018
The ‘Gene Group - Pathway Report’ is a sub-category of our Gene Group resource, which houses functional collections of genes such as complexes and gene families. ‘Pathway Reports’ list genes that have been experimentally shown to act within a pathway or to regulate a pathway. The reports are tailored to display information that may be useful to understanding the role of a particular pathway component or regulator: membership of other Gene Groups, experimentally characterized molecular functions and supporting research papers. Useful links to external resources and publications are provided, as well as options for export and orthology tools.
The ‘Pathway Report’ pages are a prelude to what will become a rich resource for researchers to access the curated data on pathway members and regulators. Our first aim is to make the list of curated pathway genes available for immediate use and review. Over 2018, we will add more pathways based on a first-pass review of the research literature. We welcome any feedback <http://flybase.org/contact/email> to help improve the usefulness and accuracy of these gene lists.
All Gene Group Pathways in FlyBase are compiled manually by FlyBase curators, based on research literature, using standards for inclusion agreed by the Gene Ontology consortium. The number of research papers that have been used as evidence for membership gene is shown in the Members table. These references can be viewed as a hitlist by clicking on the number. The number of pathway references associated with a gene may also help researchers weigh the evidence behind its inclusion. All source references are given in full at the foot of the page.
Buttons are provided to export these member genes to our ‘Batch Download’ tool, if you wish to download associated data (phenotypes, expression data, protein interactions etc.), or to a standard FlyBase HitList, if you want to further refine or analyse the gene list, or to our ortholog tool, DIOPT, to obtain a list of predicted orthologs.